Pharmaceuticals / Drug Delivery Systems

In the analysis of tablets, stents coated with active components and other media for drug administration, it is necessary to be able to determine the atomic and molecular composition with high lateral and depth resolution. In many cases, the active pharmaceutical agent and excipients must be analysed. Common issues include:

  • Structure determination of active ingredients
  • Distribution of active pharmaceutical ingredients (API) and excipients in tablets
  • Depth distribution of active ingredients in coated stents
  • Discolourations on and in tablets
  • Characterisation of impurities in tablets
  • Layer build-up in drug delivery systems
  • Diffusion of active ingredients in long term depots
  • Pollution of blister packaging

Case Studies